Alice Edith Isaacs, Marchioness of Reading, CI, GBE (ca. 1866 – 30 January 1930), née Alice Edith Cohen, was the first wife of Rufus Isaacs, 1st Marquess of Reading and a prominent philanthropist in colonial India.
The daughter of Albert Cohen, a merchant in the City of London, she married Rufus Isaacs, then a newly qualified barrister, on 8 December 1887. Her title successively changed from Mrs Isaacs to Lady Isaacs on her husband's knighthood in 1910, Baroness Reading on his ennoblement in 1914, Viscountess Reading in 1916, the Countess of Reading in 1917, and finally the Marchioness of Reading in 1926.
In 1921, Lord Reading was appointed Viceroy of India. He was reluctant to accept, as his wife's health was delicate, but she persuaded him. She accompanied him to India and, despite continuing poor health, served prominently as Viceregal Consort. She also threw herself into charitable work, particularly with Indian women and children. She established the Women of India Fund in 1921 and National Baby Week in 1923, as well as supporting many existing charities. In 1926 she campaigned to construct a standard hospital in Peshawar, in place of Agerton Hospital. The new hospital was subsequently named as Lady Reading Hospital. Later, upon the retirement of her husband in 1926, they returned to England.
She was appointed Dame Grand Cross of the Order of the British Empire (GBE) in the 1920 civilian war honours and Companion of the Order of the Crown of India (CI) on 14 March 1921, the latter being a traditional honour for the Viceregal Consort. She was awarded the Kaiser-i-Hind Medal in gold in 1924. She died of cancer in 1930.