Alexander McDonald may refer to:
Alexander McDonald (U.S. politician) (1832–1903), U.S. Senator from Arkansas
Alexander McDonald (Australian politician) (1849–1922), member of the South Australian House of Assembly
Alexander McDonald (Moderator) (born 1937), minister and moderator of the Church of Scotland
Alexander McDonald (newspaper editor) (1832–1897), editor of the Lynchburg Virginian and U.S. Minister to Persia
Alexander McDonald (Royal Marines officer) (c. 1745–1821), early land owner in New South Wales
Alexander Hamilton McDonald (1919–1980), Canadian politician
Alexander W. McDonald (1818–?), businessman and political figure in Nova Scotia, Canada
A. B. McDonald (Alexander Beith McDonald, 1847–1915), Scottish architect
