Adenosine diphosphate receptor inhibitor

Adenosine diphosphate (ADP) receptor inhibitor is a class of antiplatelet agents. These drugs inhibit some or all types of adenosine diphosphate receptors (P2Y receptors). P2Y receptors are a family of purinergic G protein-coupled receptors, stimulated by nucleotides such as ATP, ADP, UTP, UDP and UDP-glucose.

Inhibitors of the receptor subtype P2Y₁₂ are one class of P2Y receptor inhibitors. These drugs include clopidogrel, prasugrel, ticlopidine, ticagrelor, cangrelor, and elinogrel. These inhibitors prevent expression of glycoproteins IIb/IIIa on the platelet surface.