Samiksha Jaiswal (Editor)

Adaptive immunity in jawless vertebrates

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The jawless vertebrates like lamprey and hagfish have an adaptive immunity which is very similar to the one of the jawed vertebrates. There is an T-/B-Cell like lymphocyte lineage. Therefore these cells are called lymphocyte like cells (LLC). They are distinguished through the expressed receptor into the three subclasses:

  • LLCA (equivalent to α/β T cells)
  • LLCC (equivalent to γ/δ T cells)
  • LLCB (equivalent to B cells)
  • Antigen receptors

    The expressed receptor is the so-called variable lymphocyte receptor (VLR), which belongs to the leucine-rich repeat (LRR) family.

    References

    Adaptive immunity in jawless vertebrates Wikipedia