Neha Patil (Editor)

Actoxumab

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Type
  
Whole antibody

ATC code
  
none

ChemSpider
  
none

Source
  
CAS Number
  
1245634-25-6

Target
  
Clostridium difficile toxin A

Actoxumab is a human monoclonal antibody designed for the prevention of recurrence of Clostridium difficile infection.

This drug, along with bezlotoxumab, was developed through Phase II efficacy trials by a partnership between Medarex Inc and MassBiologics of the University of Massachusetts Medical School. The project was then licensed to Merck & Co., Inc. for further development and commercialization.

A study compared it with bezlotoxumab (that targets CD toxin-B) and found Actoxumab less effective.

References

Actoxumab Wikipedia


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