Acetylacetone cleaving enzyme

In enzymology, an acetylacetone-cleaving enzyme (EC 1.13.11.50) is an enzyme that catalyzes the chemical reaction

Thus, the two substrates of this enzyme are pentane-2,4-dione and O₂, whereas its two products are acetate and 2-oxopropanal.

This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O₂ as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O₂. The systematic name of this enzyme class is acetylacetone:oxygen oxidoreductase. Other names in common use include Dke1, acetylacetone dioxygenase, diketone cleaving dioxygenase, and diketone cleaving enzyme.