Girish Mahajan

Acetohydroxamic acid

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ATC code  G04BX03 (WHO)
PubChem CID  1990
ChemSpider  1913
Molar mass  75.0666 g/mol
CAS Number  546-88-3
DrugBank  DB00551
CAS ID  546-88-3
Acetohydroxamic acid
AHFS/Drugs.com  Consumer Drug Information

Acetohydroxamic acid (also known as AHA or Lithostat) is a drug that is a potent and irreversible inhibitor of bacterial and plant urease usually used for urinary tract infections. The molecule is similar to urea but is not hydrolyzable by the urease enzyme.

Orphan drug

In 1983 the US Food and Drug Administration approved acetohydroxamic acid (AHA) as an orphan drug for "prevention of so-called struvite stones" under the newly enacted Orphan Drug Act of 1983. AHA cannot be patented because it is a standard chemical compound.

References

Acetohydroxamic acid Wikipedia


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