ATC code G04BX03 (WHO) PubChem CID 1990 ChemSpider 1913 Molar mass 75.0666 g/mol | CAS Number 546-88-3 DrugBank DB00551 CAS ID 546-88-3 | |
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Acetohydroxamic acid (also known as AHA or Lithostat) is a drug that is a potent and irreversible inhibitor of bacterial and plant urease usually used for urinary tract infections. The molecule is similar to urea but is not hydrolyzable by the urease enzyme.
Orphan drug
In 1983 the US Food and Drug Administration approved acetohydroxamic acid (AHA) as an orphan drug for "prevention of so-called struvite stones" under the newly enacted Orphan Drug Act of 1983. AHA cannot be patented because it is a standard chemical compound.
References
Acetohydroxamic acid Wikipedia(Text) CC BY-SA