EC number 2.8.3.8 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 37278-35-6 BRENDA BRENDA entry KEGG KEGG entry | |
In enzymology, an acetate CoA-transferase (EC 2.8.3.8) is an enzyme that catalyzes the chemical reaction
acyl-CoA + acetateThus, the two substrates of this enzyme are acyl-CoA and acetate, whereas its two products are fatty acid anion and acetyl-CoA.
This enzyme belongs to the family of transferases, specifically the CoA-transferases. The systematic name of this enzyme class is acyl-CoA:acetate CoA-transferase. Other names in common use include acetate coenzyme A-transferase, butyryl CoA:acetate CoA transferase, butyryl coenzyme A transferase, and succinyl-CoA:acetate CoA transferase. This enzyme participates in 4 metabolic pathways: benzoate degradation via coa ligation, propanoate metabolism, butanoate metabolism, and two-component system - general.
Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1K6D.