Species Human Entrez 563 | Human Mouse Ensembl ENSG00000160862 | |
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Aliases AZGP1, ZA2G, ZAG, alpha-2-glycoprotein 1, zinc-binding External IDs MGI: 103163 HomoloGene: 915 GeneCards: AZGP1 | ||
Gene music using protein sequence of azgp1 alpha 2 glycoprotein 1 zinc binding
Zinc-alpha-2-glycoprotein is a protein that in humans is encoded by the AZGP1 gene.
This gene expresses a soluble protein that stimulates lipolysis, induces a reduction in body fat in mice, is associated with the cachexia related to cancer, and is known to be expressed in secretory cells of lung epithelium. In 2009, it was found that smoking increases expression of this gene, which is why smoking cessation leads to weight gain. Zinc-alpha-2-glycoprotein levels also rise with onset of Diabetes 2, which accounts for weight loss thereafter.
References
AZGP1 Wikipedia(Text) CC BY-SA