Species Human Entrez 6795 | Human Mouse Ensembl ENSG00000105146 | |
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Aliases AURKC, AIE2, AIK3, ARK3, AurC, SPGF5, STK13, aurora-C, HEL-S-90, aurora kinase C External IDs MGI: 1321119 HomoloGene: 68302 GeneCards: AURKC | ||
Serine/threonine-protein kinase 13 is an enzyme that in humans is encoded by the AURKC gene.
This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.
References
AURKC Wikipedia(Text) CC BY-SA