Neha Patil

AURKC

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Species  Human
Entrez  6795
Human  Mouse
Ensembl  ENSG00000105146
AURKC
Aliases  AURKC, AIE2, AIK3, ARK3, AurC, SPGF5, STK13, aurora-C, HEL-S-90, aurora kinase C
External IDs  MGI: 1321119 HomoloGene: 68302 GeneCards: AURKC

Serine/threonine-protein kinase 13 is an enzyme that in humans is encoded by the AURKC gene.

This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.

References

AURKC Wikipedia


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