|Aliases AURKC, AIE2, AIK3, ARK3, AurC, SPGF5, STK13, aurora-C, HEL-S-90, aurora kinase C|
External IDs MGI: 1321119 HomoloGene: 68302 GeneCards: AURKC
Serine/threonine-protein kinase 13 is an enzyme that in humans is encoded by the AURKC gene.
This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.