Samiksha Jaiswal

ATP5L

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Species  Human
Entrez  10632
Human  Mouse
Ensembl  ENSG00000167283
ATP5L
Aliases  ATP5L, ATP5JG, ATP synthase, H+ transporting, mitochondrial Fo complex subunit G
External IDs  MGI: 1351597 HomoloGene: 86074 GeneCards: ATP5L

ATP synthase subunit g, mitochondrial is an enzyme that in humans is encoded by the ATP5L gene.

Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, F0, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The F0 seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the g subunit of the F0 complex.

The function of subunit G is currently unknown. There is no counterpart in chloroplast or bacterial F-ATPases identified so far.

References

ATP5L Wikipedia


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