Harman Patil

ATP5J2

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Species  Human
Entrez  9551
Human  Mouse
Ensembl  ENSG00000241468
ATP5J2
Aliases  ATP5J2, ATP5JL, ATP synthase, H+ transporting, mitochondrial Fo complex subunit F2
External IDs  MGI: 1927558 HomoloGene: 3594 GeneCards: ATP5J2

The ATP5J2 gene encodes the ATP synthase subunit f, mitochondrial enzyme in humans.

Function

Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, F0, which comprises the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and single representatives of the gamma, delta, and epsilon subunits. The proton channel likely has nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the f subunit of the F0 complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

References

ATP5J2 Wikipedia


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