Puneet Varma

ATP5G3

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Species  Human
Entrez  518
Human  Mouse
Ensembl  ENSG00000154518
ATP5G3
Aliases  ATP5G3, P3, ATP synthase, H+ transporting, mitochondrial Fo complex subunit C3 (subunit 9)
External IDs  MGI: 2442035 HomoloGene: 133873 GeneCards: ATP5G3

ATP synthase lipid-binding protein, mitochondrial is an enzyme that in humans is encoded by the ATP5G3 gene.

This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene is one of three genes that encode subunit c of the proton channel. Each of the three genes have distinct mitochondrial import sequences but encode the identical mature protein. Alternatively spliced transcript variants encoding the same protein have been identified.

References

ATP5G3 Wikipedia


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