Samiksha Jaiswal

ATP5B

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Species  Human
Entrez  506
Human  Mouse
Ensembl  ENSG00000110955
ATP5B httpsmediascbtcomproduct1507z150772jpg
Aliases  ATP5B, ATPMB, ATPSB, HEL-S-271, ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
External IDs  MGI: 107801 HomoloGene: 1273 GeneCards: ATP5B

ATP synthase subunit beta, mitochondrial is an enzyme that in humans is encoded by the ATP5B gene.

Function

This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the beta subunit of the catalytic core.

References

ATP5B Wikipedia


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