Suvarna Garge

ATP synthase delta subunit

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Symbol  OSCP
InterPro  IPR000711
SCOP  1abv
Pfam  PF00213
PROSITE  PDOC00327
SUPERFAMILY  1abv
ATP synthase delta subunit

ATP synthase delta subunit is a subunit of bacterial and chloroplast ATPase, or OSCP (oligomycin sensitivity conferral protein) in mitochondrial ATPase (note that in mitochondria there is a different delta subunit, InterPro: IPR001469).

The OSCP/delta subunit appears to be part of the peripheral stalk that holds the F1 complex alpha3beta3 catalytic core stationary against the torque of the rotating central stalk, and links subunit A of the F0 complex with the F1 complex. In mitochondria, the peripheral stalk consists of OSCP, as well as F0 components F6, B and D. In bacteria and chloroplasts the peripheral stalks have different subunit compositions: delta and two copies of F0 component B (bacteria), or delta and F0 components B and B (chloroplasts).

Human delta subunit of ATP synthase is coded by gene ATP5O.

References

ATP synthase delta subunit Wikipedia


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