Girish Mahajan

APPL2

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Species  Human
Entrez  55198
Human  Mouse
Ensembl  ENSG00000136044
APPL2
Aliases  APPL2, DIP13B, adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2
External IDs  MGI: 2384914 HomoloGene: 10046 GeneCards: APPL2

DCC-interacting protein 13-beta is a protein that in humans is encoded by the APPL2 gene.

Model organisms

Model organisms have been used in the study of APPL2 function. A conditional knockout mouse line, called Appl2tm1a(KOMP)Wtsi was generated as part of the International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists — at the Wellcome Trust Sanger Institute.

Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Twenty three tests were carried out on mutant mice, but no significant abnormalities were observed.

References

APPL2 Wikipedia


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