| APPL2, DIP13B, adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2|
MGI: 2384914 HomoloGene: 10046 GeneCards: APPL2
DCC-interacting protein 13-beta is a protein that in humans is encoded by the APPL2 gene.
Model organisms have been used in the study of APPL2 function. A conditional knockout mouse line, called Appl2tm1a(KOMP)Wtsi was generated as part of the International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists — at the Wellcome Trust Sanger Institute.
Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Twenty three tests were carried out on mutant mice, but no significant abnormalities were observed.