Symbol IRES_APC RNA type Cis-reg; IRES GO 0043022 | Rfam RF00462 Domain(s) Eukaryota SO 0000243 | |
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The APC internal ribosome entry site (IRES) is an RNA element which is located in the coding sequence of the APC gene. APC is a tumour suppressor gene which is associated with the inherited disease adenomatous polyposis coli (APC). It is thought that IRES-mediated translation of APC is important for an apoptotic cascade.
References
APC internal ribosome entry site (IRES) Wikipedia(Text) CC BY-SA