| AP2S1, AP17, CLAPS2, FBH3, FBHOk, HHC3, adaptor related protein complex 2 sigma 1 subunit|
MGI: 2141861 HomoloGene: 3001 GeneCards: AP2S1
AP-2 complex subunit sigma is a protein that in humans is encoded by the AP2S1 gene.
One of two major clathrin-associated adaptor complexes, AP-2, is a heterotetramer which is associated with the plasma membrane. This complex is composed of two large chains, a medium chain, and a small chain. This gene encodes the small chain of this complex. Alternative splicing has been observed in this gene and results in two known transcripts.