Supriya Ghosh

ANP32E

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Species  Human
Entrez  81611
Human  Mouse
Ensembl  ENSG00000143401
ANP32E
Aliases  ANP32E, LANP-L, LANPL, acidic nuclear phosphoprotein 32 family member E
External IDs  HomoloGene: 137403 GeneCards: ANP32E

Acidic leucine-rich nuclear phosphoprotein 32 family member E is a protein that in humans is encoded by the ANP32E gene. The ANP32E gene is located on chromosome 1q22. In mammalian cells, ANP32E has been shown to be an H2A.Z chaperone capable of promoting the removal of H2A.Z from chromatin. In brain tissue, ANP32E together with Cpd1 regulate protein phosphatase 2A activity at synapses during synaptogenesis and has been observed to form a complex with ANP32A and SET that stabilizes short-lived mRNAs containing AU-rich elements, as well as having acetyltransferase inhibitory activity (in a complex with SET) and having a role in chromatin remodeling and transcriptional regulation.

References

ANP32E Wikipedia


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