Supriya Ghosh

ANP32C

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Species  Human
Entrez  23520
Human  Mouse
Ensembl  n/a
ANP32C
Aliases  ANP32C, PP32R1, acidic nuclear phosphoprotein 32 family member C
External IDs  HomoloGene: 49316 GeneCards: ANP32C

Acidic leucine-rich nuclear phosphoprotein 32 family member C is a protein that in humans is encoded by the ANP32C gene.

Function

Phosphoprotein 32 (PP32) is a tumor suppressor that can inhibit several types of cancers, including prostate and breast cancers. The protein encoded by this gene is one of at least two proteins that are similar in amino acid sequence to PP32 and are part of the same acidic nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been localized to a 25 amino acid region that is divergent between PP32 and the protein encoded by this gene. This gene does not contain introns.

References

ANP32C Wikipedia


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