|Aliases AMY2A, AMY2, AMY2B, PA, amylase, alpha 2A (pancreatic)|
External IDs MGI: 88019 HomoloGene: 20179 GeneCards: AMY2A
Pancreatic alpha-amylase is an enzyme that in humans is encoded by the AMY2A gene.
Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the pancreas.