CAS Number 180989-26-8 ChemSpider 8174103 Formula C23H34O3 Molar mass 358.513 g/mol | PubChem CID 10089808 ChEMBL CHEMBL127848 3D model (Jmol) Interactive image | |
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AM-906 (part of the AM cannabinoid series) is an analgesic drug which is a cannabinoid agonist. It is conformationally restricted by virtue of the double bond on its side chain, leading an increased affinity for and selectivity between CB1 and CB2 receptors. It is a potent and selective agonist for the CB1 cannabinoid receptor, with a Ki of 0.8 nM at CB1 and 9.5 nM at CB2, a selectivity of almost 12x.
The corresponding E or cis isomer is AM-905.
References
AM-906 Wikipedia(Text) CC BY-SA