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AM 411

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CAS Number  212835-02-4
ChemSpider  7975710
Formula  C26H34O2
Molar mass  378.546 g/mol
PubChem CID  9799945
3D model (Jmol)  Interactive image

AM-411 (part of the AM cannabinoid series) is an analgesic drug that is a cannabinoid agonist. It is a derivative of Δ8THC substituted with an adamantyl group at the 3-position, demonstrating that the binding pocket for the alkyl chain at this position can accommodate significant bulk.

AM-411 is a potent and fairly selective CB1 full agonist with a Ki of 6.80nM, but is still also a moderately potent CB2 agonist with a Ki of 52.0nM. It produces similar effects to other cannabinoid agonists such as analgesia, sedation, and anxiolysis.


AM-411 Wikipedia

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