|CAS Number 444912-75-8|
ECHA InfoCard 100.233.382
|PubChem CID 10226340|
Molar mass 458.334 g/mol
|Legal status CA: Schedule II DE: Anlage II (Prohibited) NZ: Temporary Class|
AM-2233 is a drug that acts as a highly potent full agonist for the cannabinoid receptors, with a Ki of 1.8 nM at CB1 and 2.2 nM at CB2 as the active (R) enantiomer. It was developed as a selective radioligand for the cannabinoid receptors and has been used as its 131I derivative for mapping the distribution of the CB1 receptor in the brain. AM-2233 was found to fully substitute for THC in rats, with a potency lower than that of JWH-018 but higher than WIN 55,212-2.
As of October 2015 AM-2233 is a controlled substance in China.