CAS Number 335160-66-2 ChemSpider 8469262 Formula C26H34N2O | PubChem CID 10293794 UNII 5EX9HEF4HK Molar mass 390.561 g/mol | |
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Legal status CA: Schedule II
NZ: Temporary Class | ||
AM-1248 is a drug that acts as a moderately potent agonist for both the cannabinoid receptors CB1 and CB2, but with some dispute between sources over its exact potency and selectivity. Replacing the 3-(1-naphthoyl) group found in many indole derived cannabinoid ligands, with an adamantoyl group, generally confers significant CB2 selectivity, but reasonable CB1 affinity and selectivity is retained when an N-methylpiperidin-2-ylmethyl substitution is used at the indole 1-position. The related compound 1-pentyl-3-(1-adamantoyl)indole was identified as having been sold as a cannabinoid designer drug in Hungary in 2011, along with another synthetic cannabinoid AM-679.
Legality
Sweden's public health agency suggested to classify AM-1248 as hazardous substance on June 1, 2015.
As of October 2015 AM-1248 is a controlled substance in China.