|CAS Number 335160-66-2|
|PubChem CID 10293794|
Molar mass 390.561 g/mol
|Legal status CA: Schedule II NZ: Temporary Class|
AM-1248 is a drug that acts as a moderately potent agonist for both the cannabinoid receptors CB1 and CB2, but with some dispute between sources over its exact potency and selectivity. Replacing the 3-(1-naphthoyl) group found in many indole derived cannabinoid ligands, with an adamantoyl group, generally confers significant CB2 selectivity, but reasonable CB1 affinity and selectivity is retained when an N-methylpiperidin-2-ylmethyl substitution is used at the indole 1-position. The related compound 1-pentyl-3-(1-adamantoyl)indole was identified as having been sold as a cannabinoid designer drug in Hungary in 2011, along with another synthetic cannabinoid AM-679.
Sweden's public health agency suggested to classify AM-1248 as hazardous substance on June 1, 2015.
As of October 2015 AM-1248 is a controlled substance in China.