Puneet Varma

ALS2CR8

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Species  Human
Entrez  79800
Human  Mouse
Ensembl  ENSG00000138380
ALS2CR8
Aliases  CARF, ALS2CR8, NYD-SP24, calcium responsive transcription factor
External IDs  MGI: 2182269 HomoloGene: 11689 GeneCards: CARF

Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein also known as calcium-response factor (CaRF) is a protein that in humans is encoded by the ALS2CR8 gene.

Knocking out the Carf (Als2cr8) gene in mice results in learning associated deficits. Furthermore, Carf has been shown to function as a transcription factor that regulates the expression of BDNF.

References

ALS2CR8 Wikipedia


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