Rahul Sharma (Editor)


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Species  Human
Entrez  79053
Human  Mouse
Ensembl  ENSG00000159063

Aliases  ALG8, CDG1H, alpha-1,3-glucosyltransferase
External IDs  MGI: 2141959 HomoloGene: 6931 GeneCards: ALG8

Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase is an enzyme that in humans is encoded by the ALG8 gene.

This gene encodes a member of the ALG6/ALG8 glucosyltransferase family. The encoded protein catalyzes the addition of the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation of proteins. Mutations in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ih). Alternatively spliced transcript variants encoding different isoforms have been identified.


ALG8 Wikipedia