Trisha Shetty


Updated on
Share on FacebookTweet on TwitterShare on LinkedIn
Species  Human
Entrez  79087
Human  Mouse
Ensembl  ENSG00000182858
Aliases  ALG12, CDG1G, ECM39, PP14673, halpha-1,6-mannosyltransferase
External IDs  MGI: 2385025 HomoloGene: 36269 GeneCards: ALG12

Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase is an enzyme that in humans is encoded by the ALG12 gene.

This gene encodes a member of the glycosyltransferase 22 family. The encoded protein catalyzes the addition of the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation. Mutations in this gene have been associated with congenital disorder of glycosylation type Ig (CDG-Ig)characterized by abnormal N-glycosylation.


ALG12 Wikipedia

Similar Topics
Victim of the Brain
Taylor Anderson
Jillian Schwartz