Neha Patil


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Species  Human
Entrez  10840
Human  Mouse
Ensembl  ENSG00000144908
Aliases  ALDH1L1, 10-FTHFDH, 10-fTHF, FDH, FTHFD, aldehyde dehydrogenase 1 family member L1
External IDs  MGI: 1340024 HomoloGene: 122031 GeneCards: ALDH1L1

10-formyltetrahydrofolate dehydrogenase is an enzyme that in humans is encoded by the ALDH1L1 gene.

The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family and is responsible for formate oxidation in vivo. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning.


ALDH1L1 Wikipedia

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