Entrez 10939 | Ensembl ENSG00000141385 | |
Aliases AFG3L2, SCA28, SPAX5, AFG3 like matrix AAA peptidase subunit 2 External IDs MGI: 1916847 HomoloGene: 4947 GeneCards: AFG3L2 |
AFG3 ATPase family gene 3-like 2 (S. cerevisiae) is a protein that in humans is encoded by the AFG3L2 gene.
This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. This gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders as well as spastic ataxia-neuropathy syndrome.
References
AFG3L2 Wikipedia(Text) CC BY-SA