Trisha Shetty (Editor)

ADP specific phosphofructokinase

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EC number
  
2.7.1.146

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
237739-62-7

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, an ADP-specific phosphofructokinase (EC 2.7.1.146) is an enzyme that catalyzes the chemical reaction

ADP + D-fructose 6-phosphate AMP + D-fructose 1,6-bisphosphate

Thus, the two substrates of this enzyme are ADP and D-fructose 6-phosphate, whereas its two products are AMP and D-fructose 1,6-bisphosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ADP:D-fructose-6-phosphate 1-phosphotransferase. This enzyme is also called ADP-6-phosphofructokinase, ADP-dependent phosphofructokinase.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1U2X.

References

ADP-specific phosphofructokinase Wikipedia