Neha Patil

ADP specific glucokinase

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EC number  2.7.1.147
IntEnz  IntEnz view
ExPASy  NiceZyme view
CAS number  173585-07-4
BRENDA  BRENDA entry
KEGG  KEGG entry
ADP-specific glucokinase

In enzymology, an ADP-specific glucokinase (EC 2.7.1.147) also known as ADP-dependent glucokinase is an enzyme that catalyzes the chemical reaction

ADP + D-glucose AMP + D-glucose 6-phosphate

Thus, the two substrates of this enzyme are ADP and D-glucose, whereas its two products are AMP and D-glucose 6-phosphate.

This enzyme belongs to the family of transferases, to be specific those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor.

In humans, the ADP-dependent glucokinase is encoded by the ADPGK gene.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1GC5.

References

ADP-specific glucokinase Wikipedia


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