EC number 2.7.1.147 ExPASy NiceZyme view | CAS number 173585-07-4 | |
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In enzymology, an ADP-specific glucokinase (EC 2.7.1.147) also known as ADP-dependent glucokinase is an enzyme that catalyzes the chemical reaction
ADP + D-glucose
Thus, the two substrates of this enzyme are ADP and D-glucose, whereas its two products are AMP and D-glucose 6-phosphate.
This enzyme belongs to the family of transferases, to be specific those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor.
In humans, the ADP-dependent glucokinase is encoded by the ADPGK gene.
Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1GC5.
References
ADP-specific glucokinase Wikipedia(Text) CC BY-SA