EC number 5.1.3.20 ExPASy NiceZyme view | CAS number 85030-75-7 | |
In enzymology, an ADP-L-glycero-D-manno-heptose 6-epimerase (EC 5.1.3.20) is an enzyme that catalyzes the chemical reaction
ADP-D-glycero-D-manno-heptose
Hence, this enzyme has one substrate, ADP-D-glycero-D-manno-heptose, and one product, ADP-L-glycero-D-manno-heptose.
This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and derivatives. The systematic name of this enzyme class is ADP-L-glycero-D-manno-heptose 6-epimerase. This enzyme participates in lipopolysaccharide biosynthesis. It employs one cofactor, NADP+ in a direct oxidation mechanism.
Structural studies
As of 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1EQ2.
References
ADP-glyceromanno-heptose 6-epimerase Wikipedia(Text) CC BY-SA