ADP dependent NAD(P)H hydrate dehydratase

Updated on Sep 29, 2024

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EC number 4.2.1.136 BRENDA BRENDA entry KEGG KEGG entry		IntEnz IntEnz view ExPASy NiceZyme view MetaCyc metabolic pathway

ADP-dependent NAD(P)H-hydrate dehydratase (EC 4.2.1.136, (6S)-beta-6-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase (ADP-hydrolysing), (6S)-6-beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase (ADP-hydrolysing, NADH-forming)) is an enzyme with systematic name (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase (ADP-hydrolysing; NADH-forming). This enzyme catalyses the following chemical reaction

(1) ADP + (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide ⇌ AMP + phosphate + NADH (2) ADP + (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide phosphate ⇌ AMP + phosphate + NADPH

This enzyme acts equally well on hydrated NADH and hydrated NADPH.

References

ADP-dependent NAD(P)H-hydrate dehydratase Wikipedia

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