Puneet Varma

ADH7

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Species  Human
Entrez  131
Human  Mouse
Ensembl  ENSG00000196344
ADH7
Aliases  ADH7, ADH4, alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
External IDs  MGI: 87926 HomoloGene: 37333 GeneCards: ADH7

Alcohol dehydrogenase class 4 mu/sigma chain is an enzyme that in humans is encoded by the ADH7 gene.

Function

This gene encodes class IV alcohol dehydrogenase 7 mu or sigma subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The enzyme encoded by this gene is inefficient in ethanol oxidation, but is the most active as a retinol dehydrogenase; thus it may participate in the synthesis of retinoic acid, a hormone important for cellular differentiation. The expression of this gene makes it much more abundant in the stomach than the liver, thus it differs from the other known gene family members.

References

ADH7 Wikipedia


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