Trisha Shetty

ADAM33

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Species  Human
Entrez  80332
Human  Mouse
Ensembl  ENSG00000149451
ADAM33
Aliases  ADAM33, C20orf153, DJ964F7.1, ADAM metallopeptidase domain 33
External IDs  MGI: 1341813 HomoloGene: 11881 GeneCards: ADAM33

Disintegrin and metalloproteinase domain-containing protein 33 is an enzyme that in humans is encoded by the ADAM33 gene.

Function

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is a type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

References

ADAM33 Wikipedia


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