Supriya Ghosh

ADAM28

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Species  Human
Entrez  10863
Human  Mouse
Ensembl  ENSG00000042980
ADAM28
Aliases  ADAM28, ADAM 28, ADAM23, MDC-L, MDC-Lm, MDC-Ls, MDCL, eMDC II, eMDCII, ADAM metallopeptidase domain 28
External IDs  MGI: 105988 HomoloGene: 40705 GeneCards: ADAM28

Disintegrin and metalloproteinase domain-containing protein 28 is an enzyme that in humans is encoded by the ADAM28 gene.

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell–cell and cell–matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a lymphocyte-expressed ADAM protein. Alternative splicing results in two transcript variants. The shorter version encodes a secreted isoform, while the longer version encodes a transmembrane isoform.

References

ADAM28 Wikipedia


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