Puneet Varma

AD 1211

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ATC code  none
CAS Number  83374-58-7
ChemSpider  26286944
Molar mass  350.496 g/mol
Synonyms  AD-1211
PubChem CID  173526
Formula  C23H30N2O
AD-1211 httpsuploadwikimediaorgwikipediacommonsthu

AD-1211 is an opioid analgesic drug invented in the 1970s by Dainippon Pharmaceutical Co. It is chemically a 1-substituted-4-prenyl-piperazine derivative, which is structurally unrelated to most other opioid drugs. The (S) enantiomers in this series are more active as opioid agonists, but the less active (R) enantiomer of this compound, AD-1211, is a mixed agonist–antagonist at opioid receptors with a similar pharmacological profile to pentazocine, and has atypical opioid effects with little development of tolerance or dependence seen after extended administration in animal studies.


AD-1211 Wikipedia

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