Rahul Sharma

ACOX3

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Aliases  ACOX3
Human  Mouse
Ensembl  ENSG00000087008
Species  Human
Entrez  8310
ACOX3
External IDs  MGI: 1933156 HomoloGene: 37792 GeneCards: ACOX3

Peroxisomal acyl-coenzyme A oxidase 3 is an enzyme that in humans is encoded by the ACOX3 gene.

Acyl-Coenzyme A oxidase 3 also known as pristanoyl -CoA oxidase (ACOX3)is involved in the desaturation of 2-methyl branched fatty acids in peroxisomes. Unlike the rat homolog, the human gene is expressed in very low amounts in the liver such that its mRNA was undetectable by routine Northern-blot analysis, by immunoblotting for its product, or by enzyme activity measurements. However the human cDNA encoding a 700 amino acid protein with a peroxisomal targeting C-terminal tripeptide S-K-L was isolated and is thought to be expressed under special conditions such as specific developmental stages or in a tissue specific manner in tissues that have not yet been examined.

References

ACOX3 Wikipedia


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