Species Human Entrez 10061 | Human Mouse Ensembl ENSG00000033050 | |
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Aliases ABCF2, ABC28, EST133090, HUSSY18, HUSSY-18, ATP binding cassette subfamily F member 2 External IDs MGI: 1351657 HomoloGene: 21408 GeneCards: ABCF2 | ||
ATP-binding cassette sub-family F member 2 is a protein that in humans is encoded by the ABCF2 gene.
Function
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This protein is a member of the GCN20 subfamily. Alternative splicing of this gene results in multiple transcript variants.
ABCF2 acts as a suppressor of the volume-sensitive outwardly rectifying Cl channel (CLCN3).
References
ABCF2 Wikipedia(Text) CC BY-SA