9 cis epoxycarotenoid dioxygenase

9-cis-epoxycarotenoid dioxygenase (EC 1.13.11.51, nine-cis-epoxycarotenoid dioxygenase, NCED, AtNCED3, PvNCED1, VP14) is an enzyme with systematic name 9-cis-epoxycarotenoid 11,12-dioxygenase. This enzyme catalyses the following chemical reaction

(1) a 9-cis-epoxycarotenoid + O2 ⇌ 2-cis,4-trans-xanthoxin + a 12'-apo-carotenal (2) 9-cis-violaxanthin + O2 ⇌ 2-cis,4-trans-xanthoxin + (3S,5R,6S)-5,6-epoxy-3-hydroxy-5,6-dihydro-12'-apo-beta-caroten-12'-al (3) 9'-cis-neoxanthin + O2 ⇌ 2-cis,4-trans-xanthoxin + (3S,5R,6R)-5,6-dihydroxy-6,7-didehydro-5,6-dihydro-12'-apo-beta-caroten-12'-al

9-cis-epoxycarotenoid dioxygenase contains iron(II).