Samiksha Jaiswal (Editor)

8 Hydroxygeraniol dehydrogenase

Updated on
Edit
Like
Comment
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
EC number
  
1.1.1.324

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

MetaCyc
  
metabolic pathway

8-hydroxygeraniol dehydrogenase (EC 1.1.1.324, 8-hydroxygeraniol oxidoreductase, CYP76B10, G10H, CrG10H, SmG10H, acyclic monoterpene primary alcohol:NADP+ oxidoreductase) is an enzyme with systematic name (6E)-8-hydroxygeraniol:NADP+ oxidoreductase. This enzyme catalyses the following chemical reaction

(6E)-8-hydroxygeraniol + 2 NADP+ ⇌ (6E)-8-oxogeranial + 2 NADPH + 2 H+ (overall reaction) (1a) (6E)-8-hydroxygeraniol + NADP+ ⇌ (6E)-8-hydroxygeranial + NADPH + H+ (1b) (6E)-8-hydroxygeraniol + NADP+ ⇌ (6E)-8-oxogeraniol + NADPH + H+ (1c) (6E)-8-hydroxygeranial + NADP+ ⇌ (6E)-8-oxogeranial + NADPH + H+ (1d) (6E)-8-oxogeraniol + NADP+ ⇌ (6E)-8-oxogeranial + NADPH + H+

This enzyme contains Zn2+. It catalyses the oxidation of (6E)-8-hydroxygeraniol to (6E)-8-oxogeranial via either (6E)-8-hydroxygeranial or (6E)-8-oxogeraniol.

References

8-Hydroxygeraniol dehydrogenase Wikipedia
(Text) CC BY-SA