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6-Hydroxymelatonin (6-OHM) is a naturally occurring, endogenous, major active metabolite of the neurotransmitter melatonin. Similar to melatonin, 6-OHM is a full agonist of the MT1 and MT2 receptors. It is also an antioxidant and neuroprotective, and is even more potent in this regard relative to melatonin.
References
6-Hydroxymelatonin Wikipedia(Text) CC BY-SA