6 Deoxy 5 ketofructose 1 phosphate synthase

6-deoxy-5-ketofructose 1-phosphate synthase (EC 2.2.1.11, DKFP synthase, MJ1585 (gene)) is an enzyme with systematic name 2-oxopropanal:D-fructose 1,6-bisphosphate glycerone-phosphotransferase. This enzyme catalyses the following chemical reaction

(1) methylglyoxal + D-fructose 1,6-bisphosphate ⇌ D-glyceraldehyde 3-phosphate + 1-deoxy-D-threo-hexo-2,5-diulose 6-phosphate(2) methylglyoxal + D-fructose 1-phosphate ⇌ D-glyceraldehyde + 1-deoxy-D-threo-hexo-2,5-diulose 6-phosphate

This enzyme plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate.