Samiksha Jaiswal (Editor)

6 APT

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Covid-19
Routes of administration  Oral
CAS Number  3160-20-1
ChemSpider  23204045
ATC code  none
PubChem CID  14964398
Molar mass  189.3 g/mol
6-APT httpsuploadwikimediaorgwikipediacommonsthu
Legal status  Uncontrolled (but may be covered under the Federal Analogue Act in the United States and under similar bills in other countries)

6-(2-Aminopropyl)tetralin (6-APT), also sometimes called tetralinylaminopropane (TAP), is a drug of the amphetamine class which acts as a selective serotonin releasing agent (SSRA). It has IC50 values of 121 nM, 6,436 nM, and 3,371 nM for inhibiting the reuptake of serotonin, dopamine, and norepinephrine, respectively. Though it possesses an appreciable in vitro profile, in animal drug discrimination studies it was not found to substitute for MMAI or amphetamine and to only partially substitute for MBDB. This parallels Alexander Shulgin's finding that EDMA (the 1,4-benzodioxine analogue of 6-APT) is inactive, and appears to indicate that the pharmacokinetics of both EDMA and 6-APT may not be favorable.

References

6-APT Wikipedia


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