Puneet Varma (Editor)

5.8S ribosomal RNA

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Covid-19
Symbol  5_8S_rRNA
RNA type  Gene; rRNA
GO  0003735 0005840
Rfam  RF00002
Domain(s)  Eukaryota; Archaea
SO  0000375
5.8S ribosomal RNA

In molecular biology the 5.8S ribosomal RNA (5.8S rRNA) is a non-coding RNA component of the large subunit of the eukaryotic ribosome and so plays an important role in protein translation. It is transcribed by RNA polymerase I as part of the 45S precursor that also contains 18S and 28S rRNA. Its function is thought to be in ribosome translocation. It is also known to form covalent linkage to the p53 tumour suppressor protein.

5.8S rRNA can be used as a reference gene for miRNA detection.

References

5.8S ribosomal RNA Wikipedia


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