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5 dehydro 4 deoxyglucarate dehydratase

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EC number
  
4.2.1.41

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
37290-77-0

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a 5-dehydro-4-deoxyglucarate dehydratase (EC 4.2.1.41) is an enzyme that catalyzes the chemical reaction

5-dehydro-4-deoxy-D-glucarate 2,5-dioxopentanoate + H2O + CO2

Hence, this enzyme has one substrate, 5-dehydro-4-deoxy-D-glucarate, but three products: 2,5-dioxopentanoate, H2O, and CO2.

Enzyme class

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is 5-dehydro-4-deoxy-D-glucarate hydro-lyase (decarboxylating 2,5-dioxopentanoate-forming). Other names in common use include 5-keto-4-deoxy-glucarate dehydratase, 5-keto-4-deoxy-glucarate dehydratase, deoxyketoglucarate dehydratase, D-4-deoxy-5-ketoglucarate hydro-lyase, and 5-dehydro-4-deoxy-D-glucarate hydro-lyase (decarboxylating). This enzyme participates in ascorbate and aldarate metabolism.

References

5-dehydro-4-deoxyglucarate dehydratase Wikipedia