EC number 5.3.3.10 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 79079-05-3 BRENDA BRENDA entry KEGG KEGG entry | |
In enzymology, a 5-carboxymethyl-2-hydroxymuconate Delta-isomerase (EC 5.3.3.10) is an enzyme that catalyzes the chemical reaction
5-carboxymethyl-2-hydroxymuconateHence, this enzyme has one substrate, 5-carboxymethyl-2-hydroxymuconate, and one product, 5-carboxy-2-oxohept-3-enedioate.
This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases transposing C=C bonds. The systematic name of this enzyme class is 5-carboxymethyl-2-hydroxymuconate Delta2,Delta4-2-oxo,Delta3-isomerase. This enzyme participates in tyrosine metabolism and benzoate degradation via hydroxylation.
Structural studies
As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes 1GTT, 1I7O, 1WZO, and 2DFU.
References
5-carboxymethyl-2-hydroxymuconate Delta-isomerase Wikipedia(Text) CC BY-SA