Suvarna Garge (Editor)

5 IAI

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Pregnancy category
  
?

CAS Number
  
132367-76-1

Molar mass
  
259.087 g/mol

ATC code
  
none

PubChem CID
  
131506

5-IAI pharmachemnetimagesstories5IAIpng

Routes of administration
  
Oral, Insufflated, Rectal

Legal status
  
In general: uncontrolled

5-Iodo-2-aminoindane (5-IAI) is a drug which acts as a releasing agent of serotonin, norepinephrine, and dopamine. It was developed in the 1990s by a team led by David E. Nichols at Purdue University. 5-IAI fully substitutes for MDMA in rodents and is a putative entactogen in humans. Unlike related aminoindane derivatives like MDAI and MMAI, 5-IAI causes some serotonergic neurotoxicity in rats, but is substantially less toxic than its corresponding amphetamine homologue pIA, with the damage observed barely reaching statistical significance.

References

5-IAI Wikipedia