Neha Patil (Editor)

5 Hydroxycytosine

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5-Hydroxycytosine httpsuploadwikimediaorgwikipediacommonsthu

5-Hydroxycytosine is an oxidized form of cytosine that is associated with an increased frequency of C to T transition mutations, with some C to G transversions. It does not distort the DNA molecule and is readily bypassed by replicative DNA polymerases.

It has been shown in vitro to miscode for adenine.

References

5-Hydroxycytosine Wikipedia


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